If you are trying to find information on the best bets in Big Ten play in Week 4, or building a parlay, our computer model is here to help. It likes betting on the over/under in the Akron vs. Indiana matchup, and picking Michigan State (+7.5) over Maryland on the spread. Find more analysis on those college football games by scrolling down.

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Best Week 4 Big Ten Spread Bets

Pick: Michigan State +7.5 vs. Maryland

  • Matchup: Maryland Terrapins at Michigan State Spartans
  • Projected Favorite & Spread: Michigan State by 6.1 points
  • Time: 3:30 PM ET
  • Date: September 23
  • TV Channel: NBC (Stream on Fubo)

Read more on the best bets for this game

Pick: Louisiana Tech +20.5 vs. Nebraska

  • Matchup: Louisiana Tech Bulldogs at Nebraska Cornhuskers
  • Projected Favorite & Spread: Nebraska by 9.7 points
  • Time: 3:30 PM ET
  • Date: September 23
  • TV Channel: BTN (Stream on Fubo)

Read more on the best bets for this game

Pick: Akron +16.5 vs. Indiana

  • Matchup: Akron Zips at Indiana Hoosiers
  • Projected Favorite & Spread: Indiana by 11.6 points
  • Time: 7:30 PM ET
  • Date: September 23
  • TV Channel: BTN (Stream on Fubo)

Read more on the best bets for this game

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Best Week 4 Big Ten Total Bets

Under 45.5 - Akron vs. Indiana

  • Matchup: Akron Zips at Indiana Hoosiers
  • Projected Total: 36 points
  • Time: 7:30 PM ET
  • Date: September 23
  • TV Channel: BTN (Stream on Fubo)

Read more on the best bets for this game

Over 38.5 - Iowa vs. Penn State

  • Matchup: Iowa Hawkeyes at Penn State Nittany Lions
  • Projected Total: 44.3 points
  • Time: 7:30 PM ET
  • Date: September 23
  • TV Channel: CBS (Stream on Fubo)

Read more on the best bets for this game

Over 44.5 - Louisiana Tech vs. Nebraska

  • Matchup: Louisiana Tech Bulldogs at Nebraska Cornhuskers
  • Projected Total: 47.8 points
  • Time: 3:30 PM ET
  • Date: September 23
  • TV Channel: BTN (Stream on Fubo)

Read more on the best bets for this game

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Week 4 Big Ten Standings

Team 2022 Record 2022 PF/G vs PA/G 2022 YDS/G vs OPP YDS/G
Ohio State 3-0 (1-0 Big Ten) 40.3 / 6.7 474.7 / 223.7
Penn State 3-0 (1-0 Big Ten) 43.7 / 11.7 467.3 / 267.3
Rutgers 3-0 (1-0 Big Ten) 31.7 / 10.0 346.3 / 272.7
Michigan 3-0 (0-0 Big Ten) 32.0 / 5.3 402.0 / 223.0
Iowa 3-0 (0-0 Big Ten) 28.3 / 12.3 302.0 / 286.0
Maryland 3-0 (0-0 Big Ten) 39.3 / 13.3 480.0 / 314.7
Wisconsin 3-1 (1-0 Big Ten) 33.3 / 19.8 427.5 / 374.8
Minnesota 2-1 (1-0 Big Ten) 17.0 / 15.7 322.3 / 322.0
Michigan State 2-1 (0-0 Big Ten) 27.7 / 20.7 377.3 / 375.0
Nebraska 1-2 (0-1 Big Ten) 19.7 / 20.0 339.3 / 284.7
Illinois 1-2 (0-1 Big Ten) 22.0 / 30.7 356.3 / 446.0
Northwestern 1-2 (0-1 Big Ten) 19.7 / 23.0 286.3 / 363.7
Indiana 1-2 (0-1 Big Ten) 19.3 / 17.0 356.0 / 298.3
Purdue 1-3 (0-1 Big Ten) 24.0 / 32.3 397.3 / 404.0

Watch Big Ten games all season long on Fubo and ESPN+!

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