Get ready for the Brother Bowl.

It'll be Harbaugh vs. Harbaugh when Big Bro John's Baltimore Ravens (13-6) play Little Bro Jim's San Francisco 49ers (13-4-1) in the Super Bowl at New Orleans in two weeks.

As much chatter as there will be about the players involved -- from Ravens linebacker Ray Lewis and his impending retirement to 49ers quarterback Colin Kaepernick's sudden emergence -- the sibling angle will make this coaching matchup the most scrutinized in the nearly half-century of Super Sundays.

On Thanksgiving Day, 2011, the Harbaughs became the first brothers to coach against each other in any NFL game. Now they'll be squaring off in the biggest one of all.

The 49ers open as 5-point favorites.