The slumping Brewers have lost 10 of their last 14 games but still lead the N-L Central by one game over the Chicago Cubs, who lost 2-1 to the Houston Astros.
Prince Fielder hit his N-L-leading 33rd homer and Ryan Braun also connected for Milwaukee.
The Rockies scored four runs off Brewers starter Claudio Vargas (9-4) in the first inning.
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