The Spurs built a 25-point halftime lead and held a double-digit lead for most of the game. The Cavaliers used a big run at the start of the fourth quarter to cut a 27-point lead to eight but that was as close as Cleveland would get.
Tony Parker led the Spurs with 30 points. Tim Duncan added 23 points, nine rebounds and eight assists.
Manu Ginobili scored 25, including a four-point play late in the game after the Cavs had cut the lead to eight.
Cavs superstar LeBron James drew two personal fouls in the opening three minutes and was benched early. He finished with 25 points.