Lifeline ambulance is moving its headquarters from Rural and Prospect in Rockford to Roxbury Drive right across the street from OSF St. Anthony's Medical Center.
Lifeline is affiliated with St. Anthony's.
Lifeline Manager Maggie Carlson says the new building will be in a more centralized location, allowing Lifeline to better serve the community.
The Roxbury location will be a 24-hour ambulance station. Lifeline also has five other substations in the area.