The Boone County Sheriff's Department says a car driven by Dennis Koser bumped into the back of another car heading east on 173 around 10:30 pm Saturday night.
The car that was hit went off the road and hit a tree. Koser's car crossed into the other lane and rammed head-on with a third car.
Koser was killed in the accident.
Amanda Springer, 17, of Poplar Grove and John Watrous, 46, of Roscoe were both taken to St. Anthony's for non-life threatening injuries.