Air Force One will land at Outagamie County Regional Airport in Greenville and Bush will be driven to Oshkosh.
The 20-mile presidential motorcade is expected to bring rush hour traffic to a halt.
Bush visit coordinator Sarah Thilman says it would have been better to land at Wittman logistically, but the regional airport was a better place to land a 7-47.
Winnebago County Executive Jane Van De Hey says county employees had been working the Secret Service, providing maps and ground plans for a Wittman landing, but she says wind velocity, taxiways at Wittman and exits caused presidential staff to set the landing at Greenville.
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